Basement Membranes: Cell Scaffoldings and Signaling Platforms
نویسندگان
چکیده
منابع مشابه
Basement membranes: cell scaffoldings and signaling platforms.
Basement membranes are widely distributed extracellular matrices that coat the basal aspect of epithelial and endothelial cells and surround muscle, fat, and Schwann cells. These extracellular matrices, first expressed in early embryogenesis, are self-assembled on competent cell surfaces through binding interactions among laminins, type IV collagens, nidogens, and proteoglycans. They form stabi...
متن کاملBasement membranes
Basement membranes (BMs) are thin, dense sheets of specialized, self-assembled extracellular matrix that surround most animal tissues (Figure 1, top). The emergence of BMs coincided with the origin of multicellularity in animals, suggesting that they were essential for the formation of tissues. Their sheet-like structure derives from two independent polymeric networks - one of laminin and one o...
متن کاملBasement membranes.
Basement membranes are thin, specialized extracellular matrices surrounding most tissues in all metazoans. The compositions and functions of basement membranes have generally been well conserved throughout the subkingdom. Genetic analyses of basement membrane components in C. elegans have provided insights into their assembly and functions during development. Immuno- or GFP-tagged localization ...
متن کاملBasement Membranes and Cell Movement. Ciba Foundation Symposium 108
choice and use of the proper antibiotic. Information on antibiotic-impregnated acrylic composites used in conjunction with systemic antibiotics is provided as well. Part three of the book essentially deals with the difficulties in management of the problematic joint replacement; the majority of this portion consists of the personal experiences of the authors. This section prov.ides commentary o...
متن کاملCell invasion through basement membranes: an anchor of understanding.
To metastasize, cancer cells must acquire the ability to breach several basement membrane barriers. Cell invasions through basement membranes also occur during normal development and immune system function, enabling organ formation and cell dispersal. The mechanisms that cells use to cross basement membranes in vivo remain elusive. In cancer and development, these invasions occur in complex and...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cold Spring Harbor Perspectives in Biology
سال: 2010
ISSN: 1943-0264
DOI: 10.1101/cshperspect.a004911